GEO series

Transcriptome-wide identification of RNA-binding protein and microRNA target sites by PAR-CLIP: QKI data

GSE21574 Homo sapiens Expression profiling by array 6 samples Submitted 2010/04/29 Platform GPL570

Summary

To assess whether the transcripts identified by PAR-CLIP are regulated by the RNA-binding protein (RBP) Quaking (QKI), we analyzed the mRNA levels of mock-transfected and QKI-specific siRNA-transfected cells with microarrays. Transcripts crosslinked to QKI were significantly upregulated upon siRNA transfection, indicating that QKI negatively regulates bound mRNAs (Figure 3H of PMID 20371350), consistent with previous reports of QKI being a repressor.

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Also filed as BioProject PRJNA129313. Searching any of these in the dataset finder brings you back here.

NCBI GEO page ↗ Paper (PMID 20371350) ↗

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