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Multiome (GEX + ATAC) profile at single cell level of Foxf1 positive endothelial cells and mesenchymal cells from mouse lung at E18.5

GSE217194 Mus musculus Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing 5 samples Submitted 2024/04/01 Platform GPL24247
Summary
Foxf1 is enriched and differentially expressed in lung cells derived from mesoderm. We used single cell RNA sequencing (snRNAseq + snATAC) to analyze the dynamic transcriptional regulation in various lung cell types. The single cell analysis show the cell specific regulation of Foxf1 by distal enhancers that contribute to the molecular pathology of ACDMPV.
Published in
Identification of endothelial and mesenchymal FOXF1 enhancers involved in alveolar capillary dysplasia
Wang G, Wen B, Guo M et al. · Nature communications 2024 · PMID 38898031 · doi:10.1038/s41467-024-49477-6
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Also filed as BioProject PRJNA897893 and SRA study SRP406117. Searching any of these in the dataset finder brings you back here.

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