GEO series
ZBTB24 is a conserved multifaceted transcription factor at genes and centromeres that governs the DNA methylation state and expression of satellite repeats [RNA-Seq]
GSE218866
Homo sapiens; Mus musculus
Expression profiling by high throughput sequencing
12 samples
2025/01/30
GPL18573GPL19057
Summary
ZBTB24 has emerged as a key player in DNA methylation, immunity and development. To explore these multiple facets of ZBTB24 functions, we performed and integrated multi-omics analyses in mouse and human cellular systems relevant for the physiopathological features of the ICF2 syndrome, a rare genetic disease caused by ZBTB24 mutations.
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Paper (PMID 39562305) ↗
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