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Transcriptome analysis of repopulated microglia after 7 days of PLX5622 treatment and 10 days of PLX5622 withdrawal

GSE220141 Mus musculus Expression profiling by high throughput sequencing 4 samples Submitted 2024/05/06 Platform GPL17021
Summary
Microglia are suspected to be a key player in several neurological diseases. Here, we investigated whether microglia depletion affects dendritic spine density after short-term microglia depletion with subsequent repopulation in the adult mouse brain.
Published in
Repopulated microglia after pharmacological depletion decrease dendritic spine density in adult mouse brain
Wickel J, Chung HY, Ceanga M et al. · Glia 2024 · PMID 38780213 · doi:10.1002/glia.24541
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Also filed as BioProject PRJNA908854 and SRA study SRP411439. Searching any of these in the dataset finder brings you back here.

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