Phase separation-competent FBL shapes nucleolar function and translation in leukemogenesis
Non-coding RNA profiling · human · 14 samples
- What it is
- Non-coding RNA profilingLevels of RNAs that do not code for proteins, such as miRNA or lncRNA.
- Organism
- Homo sapiens (human)
- Samples
- 14 samples: 6 conditions, mostly in duplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE222266_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
Also filed as BioProject PRJNA918711 and SRA study SRP416073. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 14 samples.
How we read this: 6 replicated groups read from 14 sample titles; they account for 14 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM6919265 polysome RNA CT1 polysome RNA CT
- GSM6919266 polysome RNA CT2 polysome RNA CT
- GSM6919267 polysome RNA U1 polysome RNA U
- GSM6919268 polysome RNA U2 polysome RNA U
- GSM6919269 Input RNA CT1 Input RNA CT
- GSM6919270 Input RNA CT2 Input RNA CT
- GSM6919271 Input RNA U1 Input RNA U
- GSM6919272 Input RNA U2 Input RNA U
- GSM6919273 CT1 CT
- GSM6919274 CT2 CT
- GSM6919275 CT3 CT
- GSM6919276 U1 U
- GSM6919277 U2 U
- GSM6919278 U3 U
- GSE271757 Pembrolizumab plus chemotherapy in frontline treatment of advanced epithelial ovarian cancer: clinical and translational results from a phase II trial 97 samples shares translation, phase
- GSE279065 LARP6 shapes the mRNA translation of fibrogenic genes 16 samples shares translation, shapes
- GSE260905 ALKBH1-mediated tRNA 5-formylcytidine modification facilitates codon-biased translation and leukemogenesis [RNA-seq] 12 samples shares leukemogenesis, translation
- GSE276144 LncRNAs regulate FBL to facilitate rRNA processing in cancer cells 11 samples shares fbl
- GSE288786 Human papillomavirus (HPV) infected epithelial cells and FBLN1+ fibroreticular cells govern the immunogenic tumor microenvironment in HPV-associated oropharyngeal squamous cell carcinoma 10 samples shares fbl
- GSE315651 Perfluorooctane sulfonate (PFOS) in follicular fluid and human granulosa cell dysfunction: a physiologically based toxicokinetic model translation of low-level, long-term in vitro exposure data 32 samples shares translation
- GSE295019 Lysine Methylpropionylation, a Hybrid Post-Translational Modification Mediated by p300/PCAF Couples Metabolic Dynamics with Protein Function 16 samples shares translation
- GSE307666 eIF3d and eIF3e mediate selective translational control of hypoxia that can be inhibited by small molecules 120 samples shares translation
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.