Increase of blood CSF3R+ myeloid-derived suppressor cell predicts breast cancer recurrence
RNA-seq (gene expression) · mouse · 24 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 24 samples: 24 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Increased blood CSF3R(+) myeloid-derived suppressor cell is a predictor for breast cancer recurrenceAmerican journal of cancer research · 2024
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE223029_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA924714. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 24 sample titles: 24 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM6938373 N1 at weeks 5-7 [Immune]
- GSM6938374 N2 at weeks 5-7 [Immune]
- GSM6938375 N3 at weeks 5-7 [Immune]
- GSM6938376 N1 at weeks 3 [Immune]
- GSM6938377 N2 at weeks 3 [Immune]
- GSM6938378 N3 at weeks 3 [Immune]
- GSM6938379 R1 at weeks 5-7 [Immune]
- GSM6938380 R2 at weeks 5-7 [Immune]
- GSM6938381 R3 at weeks 5-7 [Immune]
- GSM6938382 T1 at weeks 3 [Immune]
- GSM6938383 T2 at weeks 3 [Immune]
- GSM6938384 T3 at weeks 3 [Immune]
- GSM6938409 N1 at weeks 5-7 [Myeloid]
- GSM6938410 N2 at weeks 5-7 [Myeloid]
- GSM6938411 N3 at weeks 5-7 [Myeloid]
- GSM6938412 N1 at weeks 3 [Myeloid]
- GSM6938413 N2 at weeks 3 [Myeloid]
- GSM6938414 N3 at weeks 3 [Myeloid]
- GSM6938415 R1 at weeks 5-7 [Myeloid]
- GSM6938416 R2 at weeks 5-7 [Myeloid]
- GSM6938417 R3 at weeks 5-7 [Myeloid]
- GSM6938418 T1 at weeks 3 [Myeloid]
- GSM6938419 T2 at weeks 3 [Myeloid]
- GSM6938420 T3 at weeks 3 [Myeloid]
- GSE252129 Age-related Increase of CD38 Directs Osteoclastogenic Potential of Monocytic Myeloid-Derived Suppressor Cells through Mitochondrial Dysfunction 12 samples shares myeloid-derived, suppressor, increase
- GSE189382 Epithelial deletion of CUL4B increased myeloid-derived suppressor cells-mediated immunosuppression to promote ApcMin/+ tumor formation 12 samples shares myeloid-derived, suppressor, increase
- GSE318085 Sphingosine Kinase-2 Inhibition Increases Acetyl-CoA Carboxylase Activity and Phosphatidylcholine Levels to Program Immunogenicity in Myeloid-Derived Suppressor Cells [RNA-seq] 4 samples shares myeloid-derived, suppressor, increase
- GSE309615 Sphingosine Kinase-2 Inhibition Increases Acetyl-CoA Carboxylase Activity and Phosphatidylcholine Levels to Program Immunogenicity in Myeloid-Derived Suppressor Cells [ATAC-seq] 4 samples shares myeloid-derived, suppressor, increase
- GSE311155 Age- and Sex- Driven Transcriptional and Metabolic Diversity in Myeloid-Derived Suppressor Cells After Mouse Sepsis 57 samples shares myeloid-derived, suppressor
- GSE255391 Resf1 is a compound G4 quadruplex-associated tumor suppressor for triple negative breast cancer IV 16 samples shares suppressor, breast
- GSE265871 Methylation of SRSF2P95H by SETD2 suppresses myeloid-derived suppressor cell function by inhibiting inflammatory signaling in myelodysplastic syndrome 13 samples shares myeloid-derived, suppressor
- GSE295742 Mitochondrial transfer to granulocytic myeloid-derived suppressor cells augments immunosuppressive activity 12 samples shares myeloid-derived, suppressor
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.