Sex differences in Yap1 oncogene function in immune evasion
ChIP-seq / ATAC-seq (genome binding and open chromatin) · mouse · 31 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Mus musculus (mouse)
- Samples
- 31 samples: 6 conditions, mostly in triplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Male-biased Yap1-Cd276/B7-H3 axis for immune evasion in medulloblastomaCancer cell · 2026
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE223115_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA924850 and SRA study SRP417971. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 17 samples.
How we read this: 6 replicated groups read from 31 sample titles; they account for 17 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM6939849 SGm Rep.2 SGm
- GSM6939850 SGm Rep.1 SGm
- GSM6939851 SGf Rep.2 SGf
- GSM6939852 SGf Rep.1 SGf
- GSM6939853 pooled input Rep.2 pooled input
- GSM6939854 pooled input Rep.1 pooled input
- GSM6939855 YSGm
- GSM6939856 YSGf
- GSM6939857 SGm SGm
- GSM6939858 SGf SGf
- GSM6939859 SG.1 SG
- GSM6939860 SG.2 SG
- GSM6939861 SG.3 SG
- GSM6939862 YSGr.1 YSG
- GSM6939863 YSGr.2 YSG
- GSM6939864 YSGr.3 YSG
- GSM6939865 YSGnr.1 YSGn
- GSM6939866 YSGnr.2 YSGn
- GSM6939867 YSGnr.3 YSGn
- GSM6939868 EP.SG [Yun.Yp.1]
- GSM6939869 EP.SG [Yun.Yp.2]
- GSM6939870 EP.SG [Yun.Yp.3]
- GSM6939871 EP.SG [Yun.Yp.4]
- GSM6939872 EP.SG [Yun.Yp.5]
- GSM6939873 EP.SG [Yun.Yp.6]
- GSM6939874 EP.YSGr [Yun.Yp.7]
- GSM6939875 EP.YSGr [Yun.Yp.8]
- GSM6939876 EP.YSGr [Yun.Yp.9]
- GSM6939877 EP.YSGr [Yun.Yp.10]
- GSM6939878 EP.YSGr [Yun.Yp.11]
- GSM6939879 EP.YSGr [Yun.Yp.12]
- GSE223114 Sex differences in Yap1 oncogene function in immune evasion [EndPoint_Bulk RNA-seq] 12 samples shares yap1, differences, oncogene, evasion
- GSE269007 YAP1 is a key regulator of EWS::FLI1-dependent malignant transformation upon IGF-1 mediated reprogramming of bone mesenchymal stem cells 27 samples shares yap1
- GSE262620 Hepatic Yap1 activates systemic catabolism and muscle loss during organ repair: evidence for a common mechanism with cancer cachexia 36 samples shares yap1
- GSE53167 Yap1 activation enables bypass of oncogenic Kras addiction in pancreatic cancer (part 1) 36 samples shares yap1
- GSE274111 Effect of the depletion of YAP1 in adult spinal cord neural stem cells 20 samples shares yap1
- GSE274930 ZMAT1 promotes osteoclast formation and bone loss through TRIM46 mediated YAP1 degradation II 18 samples shares yap1
- GSE269006 YAP1 is a key regulator of EWS::FLI1-dependent malignant transformation upon IGF-1 mediated reprogramming of bone mesenchymal stem cells [RNA-seq] 15 samples shares yap1
- GSE274540 ZMAT1 promotes osteoclast formation and bone loss through TRIM46 mediated YAP1 degradation. 15 samples shares yap1
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.