GEO series
RNA-seq analysis of DLBCL cell lines in response to chemotherapy
GSE224867
Homo sapiens
Expression profiling by high throughput sequencing
36 samples
2024/10/29
GPL20301
Summary
Despite the long-standing role of standard chemotherapy in human diffuse large B cell lymphoma (DLBCL), the basis for individual tumor responses and how they associate with different transcriptional programs are incompletely understood. Hence we aimed to classify DLBCL cell lines by their ability to undergo therapy-induced senescence (TIS) in response to adriamycin (aka doxorubicin) and acquire gene expression profiles before and after chemotherapy by RNA-seq.
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Paper (PMID 40159497) ↗
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