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Subcommissural organ (SCO) contributes to brain development via SCO-secreted peptides.

GSE226349 Mus musculus Expression profiling by high throughput sequencing 16 samples 2024/11/30 GPL30215
Summary
To explore the mechanism of SCO-derived peptides, we performed RNAseq in cultured neurons added with SCO peptide and control neurons which added with DPBS to identify the expression of some unique genes and possible pathway related to the function of SCO derived peptides. We cofirmed the role of SCO derived peptide which contribute in neuronal development,especially projection developent and cell survival. development and neuronal survival .
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