Transcriptomic analysis of enamel organ in a mouse model of Loeys-Dietz Syndrome Type II harboring a G357W mutation in the Tgfbr2 gene
RNA-seq (gene expression) · mouse · 13 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 13 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Distinctive Amelogenesis Imperfecta in Loeys-Dietz Syndrome Type IIJournal of dental research · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE226610_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA940801 and SRA study SRP425560. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 13 more — browse all 13 samples with per-sample file links →
- GSE284226 Transcriptomic analysis of first molars in a mouse model of Loeys-Dietz Syndrome Type II harboring a G357W mutation in the Tgfbr2 gene 22 samples shares tgfbr2, g357w, loeys-dietz, harboring, mutation, type
- GSE226611 Transcriptomic analysis of young aortic tissue in a mouse model of Loeys-Dietz Syndrome Type II harboring a G357W mutation in the Tgfbr2 gene 11 samples shares tgfbr2, g357w, loeys-dietz, harboring, mutation, type
- GSE301156 Control and Tgfbr2 cKO Mouse Endometrial Epithelial Organoids +/- E2/MPA Treatment 16 samples shares tgfbr2, organ
- GSE299064 PAM-flexible adenine base editing rescues hearing loss in a humanized MPZL2 mouse model harboring an East Asian founder mutation 9 samples shares harboring, mutation
- GSE255810 Transcriptional profiling of mouse embryonic fibroblasts harboring the Fxn G127V mutation 6 samples shares harboring, mutation
- GSE275791 IDH-mutant glioma arises from glial progenitor cells harboring the initial driver mutation 2 samples shares harboring, mutation
- GSE198654 RNA Sequencing of Mrp8-Cre;TGFbR2-fl/fl Lung Neutrophils 6 samples shares tgfbr2
- GSE295782 Diversity and immune dynamics of choroid plexus macrophages are shaped by distinct developmental origins [scRNA-seq Tgfbr2_cKO] 2 samples shares tgfbr2
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.