Investigating ovarian disrupting effects of per- and polyfluoroalkyl substances
RNA-seq (gene expression) · mouse · 44 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 44 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Exposure to Long- and Short-Chain Per- and Polyfluoroalkyl Substances in Mice and Ovarian-Related Outcomes: An in Vivo and in Vitro StudyEnvironmental health perspectives · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE227267_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA944257 and SRA study SRP427093. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 44 more — browse all 44 samples with per-sample file links →
- GSE337368 Investigating the effects of IFN-gamma on attached and detached ovarian cancer cells 24 samples shares investigating, ovarian
- GSE284229 Per- and polyfluoroalkyl substances (PFAS) suppress macrophage alternative activation to disrupt hepatic lipid metabolism [RNA-seq II] 24 samples shares polyfluoroalkyl, substances
- GSE303480 Broad Profiling of Hepatic and Immunotoxic Effects of Per- and Polyfluoroalkyl Substances (PFASs) Across Sexes and Exposure Durations in C57/BL6 Mice 116 samples shares polyfluoroalkyl, substances
- GSE271479 Sperm production is comprised in mice exposed to environmentally relevant per- and polyfluoroalkyl substances (PFAS) 19 samples shares polyfluoroalkyl, substances
- GSE233544 Investigating T cell responses in the dura to systemic infection 58 samples shares investigating
- GSE294660 Obesity promotes urinary tract infection by disrupting urothelial immune defenses 28 samples shares disrupting
- GSE261822 Investigating Immune Escape of Chronic Myeloid Leukemia in Blast Crisis by Comparing T cells from miR-142 KO BCR-ABL versus miR-142 WT BCR-ABL mice 24 samples shares investigating
- GSE275887 Investigating the potential molecular mechanisms of mogroside V on glucose homeostasis by transcriptome profiling of adult mouse hypothalamic cells 24 samples shares investigating
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.