GEO series
Disrupting tRNA modifications to target mitochondrial vulnerabilities in drug-resistant leukemia cells
GSE228208
Homo sapiens
Expression profiling by high throughput sequencing
48 samples
2025/08/19
GPL24676
Summary
To comprehensively identify cancer-relevant RNA modifications and their regulators, we screened all 150 known human RNA modifying proteins across 18 different normal and cancer lines using a CRISPR-based genetic knockout system.
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Paper (PMID 40749163) ↗
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