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Gene expression profile of overgrown livers from genetic models involving YAP or MYC overexpression.

GSE228863 Mus musculus Expression profiling by high throughput sequencing 12 samples 2024/04/01 GPL19057
Summary
We reasoned that when livers grow beyond their normal size, some growth regulating secreted factors will be suppressed and others will be overexpressed. To obtain overgrown livers, we used genetic models involving YAP or MYC overexpression We the identified differentially expressed genes in both models and filtered out secreted factors by bioinformatically defined secreted protein list.
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