Discrimination of direct HIV-1 Tat effects and compensatory reactions of cultured B cells by RNA-seq analysis
RNA-seq (gene expression) · human · 12 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 12 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Compensatory reactions of B cells in response to chronic HIV-1 Tat exposureJournal of cellular physiology · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE233499_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA976359 and SRA study SRP439629. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 12 more — browse all 12 samples with per-sample file links →
- GSE275260 Total RNA-seq analysis of WT and Gag chimera HIV-1 virions 62 samples shares hiv-1, rna-seq
- GSE280360 The p400 complex promotes HIV-1 latency by suppressing 1 viral transcription and altering the host cell state [RNA-seq] 52 samples shares hiv-1, rna-seq
- GSE329693 Microbiome-Derived Metabolites Shape CD4⁺ T-Cell Differentiation and Immune Aging in Chronic HIV-1 Infection [RNA-Seq] 36 samples shares hiv-1, rna-seq
- GSE256089 scRNA-seq analyses of HTO-tagged human peripheral blood mononuclear cells collected at the ART timepoint during HIV-1 disease 32 samples shares hiv-1, rna-seq
- GSE282545 Intracellular HIV-1 Tat regulator induces epigenetic changes in the DNA methylation landscape [RNA-seq] 12 samples shares hiv-1, rna-seq
- GSE267988 Transcription of HIV-1 at sites of intact latent provirus integration [scRNA-seq] 10 samples shares hiv-1, rna-seq
- GSE328611 Microbiome-Derived Metabolites Shape CD4⁺ T-Cell Differentiation and Immune Aging in Chronic HIV-1 Infection [scRNA-seq] 6 samples shares hiv-1, rna-seq
- GSE325054 Time-Resolved Multi-Omics Identify Biomarkers of Immediate Reactions to mRNA Vaccination [RNA-Seq] 187 samples shares reactions, rna-seq
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.