Effect of nicotinamide mononucleotide on doxorubicin-induced cardiac injury in mice
RNA-seq (gene expression) · mouse · 16 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 16 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE233644_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA977218 and SRA study SRP440022. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 16 more — browse all 16 samples with per-sample file links →
- GSE227189 Single cell transcriptomic analyses of the dynamic local and systemic response to cardiac injury in mice and zebrafish [mouse] 28 samples shares cardiac, injury
- GSE232098 Innate immune memory after brain injury drives inflammatory cardiac dysfunction 20 samples shares cardiac, injury
- GSE285475 Endothelial transcription factor EB protects against doxorubicin-induced endothelial toxicity and cardiac dysfunction 18 samples shares doxorubicin-induced, cardiac
- GSE316860 TLR7 - ITGAM: A NOVEL INNATE IMMUNE PATHWAY IN CARDIAC ISCHEMIC INJURY [snRNA-Seq] 9 samples shares cardiac, injury
- GSE245987 Vascular endothelial S1PR2 aggravates cardiac ischemia/reperfusion injury through triggering mitochondrial dysfunctions and endothelial pyroptosis via RHO/ROCK1/DRP1/NLRP3 pathway [heart] 4 samples shares cardiac, injury
- GSE232327 Activation of imprinted gene Pw1 promotes cardiac fibrosis after ischemic injury 41 samples shares cardiac, injury
- GSE248653 Nicotinamide mononucleotide promotes female germline stem cell proliferation by activating the H4K16ac-Hmgb1-Fyn-PLD signaling pathway through epigenetic remodeling 20 samples shares mononucleotide, nicotinamide
- GSE309251 Western diet-induced MASH in PWK/PhJ mice identifies disruptions in amino acid and sphingolipid metabolism contributing to cardiac dysfunction 347 samples shares cardiac
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.