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Detailed analysis of the murine-aged brain transcriptome [ONT]

GSE233836 Mus musculus Expression profiling by high throughput sequencing 8 samples Submitted 2024/03/13 Platform GPL24973
Summary
In this work, we collected and analyzed two cohorts of young-adult and aged-adult mice brain mRNAs and determined their levels using second- (illumina) and third-generation (Oxford Nanopore) sequencing technologies. We report a transcriptome-wide study of differential transcript usage during brain aging. In addition, we provide the community with a large resource of whole brain transcriptomes and comprehensive analyses that identify widespread diversity of mRNAs during aging.
Published in
Comprehensive transcriptome analysis reveals altered mRNA splicing and post-transcriptional changes in the aged mouse brain
Kumar NH, Kluever V, Barth E et al. · Nucleic acids research 2024 · PMID 38471806 · doi:10.1093/nar/gkae172
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Also filed as BioProject PRJNA978072 and SRA study SRP440496. Searching any of these in the dataset finder brings you back here.

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