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Effect of Atractylodin on high fat diet-induced fatty liver disease

GSE234666 Mus musculus Expression profiling by high throughput sequencing 6 samples Submitted 2024/11/13 Platform GPL21626
Summary
The escalating prevalence of metabolic diseases, driven by the rapid increase in obesity rates, necessitates effective therapeutic strategies. Insulin resistance and nonalcoholic fatty liver disease represent significant metabolic disorders. Atractylodin exhibits anti-inflammatory and antioxidant properties, suggesting potential hepatoprotective effects against acute liver damage. As therapeutic interventions for nonalcoholic steatohepatitis are lacking, this study aims to elucidate the pharmacological impact of Atractylodin on lipid and glucose metabolism.
Published in
Atractylodes Lancea and Its Constituent, Atractylodin, Ameliorates Metabolic Dysfunction-Associated Steatotic Liver Disease via AMPK Activation
Song GY, Kim SM, Back S et al. · Biomolecules & therapeutics 2024 · PMID 39391981 · doi:10.4062/biomolther.2024.083
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Also filed as BioProject PRJNA982728 and SRA study SRP442844. Searching any of these in the dataset finder brings you back here.

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