← BioTransfer GEO Dataset Finder
GEO series

Single cell transcriptional analysis of regenerating parietal cells (PCs) in murine gastric epithelium recovering from Diphtheria toxin injury

GSE236098 Mus musculus Expression profiling by high throughput sequencing 5 samples Submitted 2024/05/01 Platform GPL24247
Summary
Highly specialized, acid-secreting PCs are one of many epithelial lineages that line the gastric epithelium. Even though PCs are functionally and structurally distinct from other lineages in the stomach, the molecular mechanisms that govern their specification and maturation from the gastric stem cells are relatively unknown. We used single cell RNA sequencing (scRNA-seq) to construct a transcriptional profile for regenerating PCs and identify candidate regulators of PC fate specification and maturation.
Published in
Metabolic regulator ERRγ governs gastric stem cell differentiation into acid-secreting parietal cells
Adkins-Threats M, Arimura S, Huang YZ et al. · Cell stem cell 2024 · PMID 38733994 · doi:10.1016/j.stem.2024.04.016
This dataset
Download

Direct links to NCBI, no account and no request form: the whole study as GSE236098_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 5 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA988965 and SRA study SRP446485. Searching any of these in the dataset finder brings you back here.

Samples in this study

The sample list for this study is not cached yet. Press Sort into groups and it will be fetched from NCBI.

+ 5 more — browse all 5 samples with per-sample file links →

Similar datasets

Search all mouse RNA-seq datasets in GEO →

Share this dataset

Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.