GEO series
Bulk RNA sequencing of CD8a+ and CD8a- CD56bright and CD56dim human NK cells
GSE236394
Homo sapiens
Expression profiling by high throughput sequencing
23 samples
2024/07/17
GPL24676
Summary
In patients treated with memory-like NK cellular therapy with AML, a negative association with CD8a expression on donor NK cells and treatment response was found. The goal of this project was to determine how this finding extended to conventional NK cells, and to characterize the expression and functional role of CD8a. Peripheral blood NK cells were sorted on CD8 expression and analyzed by bulk RNA sequencing within CD56bright and CD56dim NK cell subsets.
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Paper (PMID 38805302) ↗
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