miR-146b-5p downregulates IRAK1 and ADAM19 to suppress trophoblast proliferation, invasion and migration in miscarriage [circRNA, lincRNA, and mRNA profiles]
Non-coding RNA profiling · human · 10 samples
- What it is
- Non-coding RNA profilingLevels of RNAs that do not code for proteins, such as miRNA or lncRNA.
- Organism
- Homo sapiens (human)
- Samples
- 10 samples: 5 × normal pregnancyGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Identification of important genes related to ferroptosis in early missed abortion based on WGCNAScientific reports · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE237732_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
Also filed as BioProject PRJNA996514 and SRA study SRP450371. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 5 samples.
How we read this: 1 replicated groups read from 10 sample titles; they account for 5 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7646269 normal pregnancy 1 [57] normal pregnancy
- GSM7646270 normal pregnancy 2 [58] normal pregnancy
- GSM7646271 normal pregnancy 3 [59] normal pregnancy
- GSM7646272 normal pregnancy 4 [60] normal pregnancy
- GSM7646273 normal pregnancy 5 [61] normal pregnancy
- GSM7646274 recurrent miscarriage 1 [T11]
- GSM7646275 recurrent miscarriage 2 [T19]
- GSM7646276 recurrent miscarriage 3 [T20]
- GSM7646277 recurrent miscarriage 4 [T5]
- GSM7646278 recurrent miscarriage 5 [T8]
- GSE237734 miR-146b-5p downregulates IRAK1 and ADAM19 to suppress trophoblast proliferation, invasion and migration in miscarriage. 20 samples shares adam19, irak1, downregulates, proliferation, mir-146b-5p, trophoblast, miscarriage, migration
- GSE232079 Targeting the Epigenome Reduces Keloid Fibroblast Cell Proliferation, Migration and Invasion 28 samples shares proliferation, migration
- GSE298356 Endothelins positively influences the proliferation vs migration balance of IDH1-mutant glioma cells and promotes proneural to mesenchymal transition [RNAseq-275HUVEC] 12 samples shares proliferation, migration
- GSE119196 HOXC10 Overexpression Promotes Cell Proliferation and Migration through Regulation of CST1 Expression in Gastric Cancer 2 samples shares proliferation, migration
- GSE178402 LncRNA HIF1A-AS1 regulates the apoptosis and proliferation of vascular endothelial cells through globally regulating miRNAs expression 24 samples shares proliferation
- GSE299960 Increased LEF1 protein levels and isoform switching drive cell proliferation in chronic lymphocytic leukemia [CUT&Run] 70 samples shares proliferation
- GSE278330 Systemic IL-23 blockade downregulates IL-23 receptor-expressing Type 17 T-cell subsets and upregulates regulatory gene expression in myeloid cells in human psoriasis skin 63 samples shares downregulates
- GSE313416 Transient proliferation by reversible YAP- and mitogen-control of the cyclin D1/p27 ratio 63 samples shares proliferation
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.