GEO series
Effect of KDM5 histone demethylase in 3T3-L1 differentiation
GSE239950
Mus musculus
Expression profiling by high throughput sequencing
29 samples
2024/03/04
GPL24247
Summary
The KDM5 histone demethylases regulate histone methylation to modulate chromatin structure and gene expression. Using a KDM5 enzyme inhibitor (KDM5-C70) and transcriptome profiling by RNA-sequencing in 3T3-L1 cells at different states of differentiation, we determined that KDM5 activity influences the induction of genes associated with cell cycle regulation and mitochondrial function.
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Paper (PMID 38425435) ↗
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