GEO series
Regulation of GLIS3 in neonatal kidney development
GSE240532
Mus musculus
Expression profiling by high throughput sequencing
24 samples
2024/12/18
GPL19057GPL24247
Summary
Loss of transcription factor GLIS3 function in humans and mice leads to the development of neonatal polycystic kidney disease (PKD). To investigate how loss of GLIS3 function in kidney affects postnatal kidney development and PKD, we analyzed the gene expression profiles of kidneys from WT and Glis3-null mice at P7, P14, and P28 by RNA-Seq analysis using Glis3 global KO model Glis3-mCherry.
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Paper (PMID 39505148) ↗
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