Loss of skeletal muscle Bmal1 +/- Exercise Training
RNA-seq (gene expression) · mouse · 20 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 20 samples: 5 × Vehicle Control vs 5 × iMSBmal1KO Control vs 5 × Vehicle Exercise Trained vs 5 × iMSBmal1KO Exercise TrainedGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Skeletal muscle BMAL1 is necessary for transcriptional adaptation of local and peripheral tissues in response to endurance exercise trainingMolecular metabolism · 2024
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE240653_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1004572 and SRA study SRP454637. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 20 samples.
How we read this: 4 replicated groups read from 20 sample titles; they account for 20 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7706802 Vehicle Control 1 Vehicle Control
- GSM7706803 Vehicle Control 2 Vehicle Control
- GSM7706804 Vehicle Control 3 Vehicle Control
- GSM7706805 Vehicle Control 4 Vehicle Control
- GSM7706806 Vehicle Control 5 Vehicle Control
- GSM7706807 iMSBmal1KO Control 1 iMSBmal1KO Control
- GSM7706808 iMSBmal1KO Control 2 iMSBmal1KO Control
- GSM7706809 iMSBmal1KO Control 3 iMSBmal1KO Control
- GSM7706810 iMSBmal1KO Control 4 iMSBmal1KO Control
- GSM7706811 iMSBmal1KO Control 5 iMSBmal1KO Control
- GSM7706812 Vehicle Exercise Trained 1 Vehicle Exercise Trained
- GSM7706813 Vehicle Exercise Trained 2 Vehicle Exercise Trained
- GSM7706814 Vehicle Exercise Trained 3 Vehicle Exercise Trained
- GSM7706815 Vehicle Exercise Trained 4 Vehicle Exercise Trained
- GSM7706816 Vehicle Exercise Trained 5 Vehicle Exercise Trained
- GSM7706817 iMSBmal1KO Exercise Trained 1 iMSBmal1KO Exercise Tra…
- GSM7706818 iMSBmal1KO Exercise Trained 2 iMSBmal1KO Exercise Tra…
- GSM7706819 iMSBmal1KO Exercise Trained 3 iMSBmal1KO Exercise Tra…
- GSM7706820 iMSBmal1KO Exercise Trained 4 iMSBmal1KO Exercise Tra…
- GSM7706821 iMSBmal1KO Exercise Trained 5 iMSBmal1KO Exercise Tra…
- GSE253735 Loss of skeletal muscle Bmal1 +/- Exercise Training [Mouse liver, heart, inguinal white adipose and lung tissues 64 samples shares bmal1, skeletal, exercise, training, muscle, loss
- GSE325919 Mitochondrial remodeling in skeletal muscle underlies exercise-induced reversal of age-associated functional decline in mice and humans 30 samples shares skeletal, exercise, muscle
- GSE324100 Exercise Training Prior To and During Cancer in Mice Preserves Muscle Mass, Reduces Tumor Weight, and Suppresses Molecular Mediators of Cachexia 22 samples shares exercise, training, muscle
- GSE326952 Semaglutide-induced Loss of Skeletal Muscle Mass is Blunted by Co-administration of Ketone Esters 13 samples shares skeletal, muscle, loss
- GSE232957 Muscle-specific rescue of Bmal1 impacts survival and health span of the Bmal1-KO mouse 72 samples shares bmal1, muscle
- GSE237747 Transcriptomic profiling across 20 CC-RIX genetic backgrounds with and without high-fat high-sugar (HFHS) diet, and with and without metformin [skeletal muscle] 703 samples shares skeletal, muscle
- GSE267727 Transcriptome profiling of non-islet metabolic tissues in ~500 DO mouse liver, adipose, heart, and skeletal muscle tissue from mice fed high-fat, high-sugar diet [heart] 482 samples shares skeletal, muscle
- GSE266549 Transcriptome profiling of non-islet metabolic tissues in ~500 DO mouse liver, adipose, and skeletal muscle tissue from mice fed high-fat, high-sugar diet. [Adipose] 468 samples shares skeletal, muscle
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.