First cleavage is a manifestation of the geometry of the unfertilized oocyte: implications for monozygotic twinning in mice.
RNA-seq (gene expression) · mouse · 219 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 219 samples: 219 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Animal and vegetal materials of mouse oocytes segregate at first zygotic cleavage: a simple mechanism that makes the two-cell blastomeres differ reciprocally from the startMolecular human reproduction · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE241089_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1006384 and SRA study SRP455625. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 219 sample titles: 219 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7715194 ICSI_Co_1a, blastomere, scRNA-seq
- GSM7715195 ICSI_Co_1b, blastomere, scRNA-seq
- GSM7715196 ICSI_Co_2a, blastomere, scRNA-seq
- GSM7715197 ICSI_Co_2b, blastomere, scRNA-seq
- GSM7715198 ICSI_Co_3a, blastomere, scRNA-seq
- GSM7715199 ICSI_Co_3b, blastomere, scRNA-seq
- GSM7715200 ICSI_Co_4a, blastomere, scRNA-seq
- GSM7715201 ICSI_Co_4b, blastomere, scRNA-seq
- GSM7715202 ICSI_Co_5a, blastomere, scRNA-seq
- GSM7715203 ICSI_Co_5b, blastomere, scRNA-seq
- GSM7715204 ICSI_Co_6a, blastomere, scRNA-seq
- GSM7715205 ICSI_Co_6b, blastomere, scRNA-seq
- GSM7715206 ICSI_Co_7a, blastomere, scRNA-seq
- GSM7715207 ICSI_Co_7b, blastomere, scRNA-seq
- GSM7715208 ICSI_Co_8a, blastomere, scRNA-seq
- GSM7715209 ICSI_Co_8b, blastomere, scRNA-seq
- GSM7715210 ICSI_Co_9a, blastomere, scRNA-seq
- GSM7715211 ICSI_Co_9b, blastomere, scRNA-seq
- GSM7715212 ICSI_Co_10a, blastomere, scRNA-seq
- GSM7715213 ICSI_Co_10b, blastomere, scRNA-seq
- GSM7715214 ICSI_Co_11a, blastomere, scRNA-seq
- GSM7715215 ICSI_Co_11b, blastomere, scRNA-seq
- GSM7715216 ICSI_Co_12a, blastomere, scRNA-seq
- GSM7715217 ICSI_Co_12b, blastomere, scRNA-seq
- GSM7715218 ICSI_Co_13a, blastomere, scRNA-seq
- GSM7715219 ICSI_Co_13b, blastomere, scRNA-seq
- GSM7715220 ICSI_Co_14a, blastomere, scRNA-seq
- GSM7715221 ICSI_Co_14b, blastomere, scRNA-seq
- GSM7715222 ICSI_Co_15a, blastomere, scRNA-seq
- GSM7715223 ICSI_Co_15b, blastomere, scRNA-seq
- GSM7715224 ICSI_Is_16a, blastomere, scRNA-seq
- GSM7715225 ICSI_Is_16b, blastomere, scRNA-seq
- GSM7715226 ICSI_Is_17a, blastomere, scRNA-seq
- GSM7715227 ICSI_Is_17b, blastomere, scRNA-seq
- GSM7715228 ICSI_Is_18a, blastomere, scRNA-seq
- GSM7715229 ICSI_Is_18b, blastomere, scRNA-seq
- GSM7715230 ICSI_Is_19a, blastomere, scRNA-seq
- GSM7715231 ICSI_Is_19b, blastomere, scRNA-seq
- GSM7715232 ICSI_Is_20a, blastomere, scRNA-seq
- GSM7715233 ICSI_Is_20b, blastomere, scRNA-seq
+ 179 more — browse all 219 samples with per-sample file links →
- GSE300410 Parental preconceptual α-cypermethrin exposure alters embryonic brain transcriptomics in mice: implications for autism spectrum disorder and stress vulnerability 76 samples shares implications
- GSE298247 Docosahexaenoic Acid Enhances Dexamethasone-Mediated Suppression of Interferon-Regulated Genes in NZBWF1 Macrophages: Implications for Steroid-Sparing Lupus Treatment 36 samples shares implications
- GSE263678 Time‑course analysis of cisplatin induced AKI in preclinical models: implications for testing different sources of MSCs 32 samples shares implications
- GSE319717 Implications for postpartum reprograming of SEMA7A and SOX9 in mammary cells and breast cancer 24 samples shares implications
- GSE268171 Role of iRhom2 in Olfaction: Implications for Odorant Receptor Regulation and Activity-dependent Adaptation 24 samples shares implications
- GSE301439 Effects of Oxaliplatin on Hematopoietic Pathways with Implications for Chronic Pain 20 samples shares implications
- GSE296094 Genomic stratification based on SMAD4 in pancreatic cancer reveals biological implications of aberrant TGFβ signaling and susceptibility to TGFβ inhibition 20 samples shares implications
- GSE299632 Elevated expression of the molecular clock suppressors Period 1 and Period 2 promote myotube atrophy in vitro with implications to the loss of limb muscle mass following androgen deprivation 20 samples shares implications
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.