Multi-OMIC analysis of Huntington disease reveals a neuroprotective astrocyte state
RNA-seq (gene expression) · human · 156 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 156 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Multi-omic analysis of Huntington's disease reveals a compensatory astrocyte stateNature communications · 2024
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE242198_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1011946 and SRA study SRP458058. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 156 more — browse all 156 samples with per-sample file links →
- GSE242195 Multi-OMIC analysis of Huntington disease reveals a neuroprotective astrocyte state (bulk RNA-Seq) 91 samples shares neuroprotective, multi-omic, huntington, astrocyte, state
- GSE242197 Multi-OMIC analysis of Huntington disease reveals a neuroprotective astrocyte state (snRNA-Seq) 65 samples shares neuroprotective, multi-omic, huntington, astrocyte, state
- GSE288562 Multi-Omics Analysis of the Immunological State at Baseline and Following SARS-CoV-2 mRNA Vaccination in Lung Transplant Recipients 14 samples shares multi-omic, state
- GSE282511 Multi-omics analysis in primary T cells elucidates mechanisms behind disease associated genetic loci [RNA-seq] 128 samples shares multi-omic
- GSE289574 Multi-omics Analysis of Skeletal Muscle Identifies Dysregulation of Hypoxia-Induced Genes in Peripheral Artery Disease [RNA-seq] 40 samples shares multi-omic
- GSE268599 Astrocyte transcriptomic changes along the spatiotemporal progression of Alzheimer’s disease 146 samples shares astrocyte
- GSE319130 Multi-omic analysis reveals molecular subtypes with distinct immunological phenotypes in SLE [RNA-Seq] 804 samples shares multi-omic
- GSE338964 Computational modeling and preclinical evaluation support targeting somatic instability for Huntington’s disease treatment. 104 samples shares huntington
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.