Activated-ATF6α is an ER stress-inducing oncoprotein metabolically restricting immunosurveillance
RNA-seq (gene expression) · mouse · 38 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 38 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Activated ATF6α is a hepatic tumour driver restricting immunosurveillanceNature · 2026
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE244344_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1022432 and SRA study SRP463871. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 38 more — browse all 38 samples with per-sample file links →
- GSE244342 Activated-ATF6α is an ER stress-inducing oncoprotein metabolically restricting immunosurveillance [bulk RNA-seq of TG-AAV-GFP/CRE, DEN/HFD] 16 samples shares immunosurveillance, stress-inducing, activated-atf6, metabolically, oncoprotein, restricting
- GSE244341 Activated-ATF6α is an ER stress-inducing oncoprotein metabolically restricting immunosurveillance [bulk RNAseq of TG-AAV-GFP/CRE/FBP1] 16 samples shares immunosurveillance, stress-inducing, activated-atf6, metabolically, oncoprotein, restricting
- GSE244343 Activated-ATF6α is an ER stress-inducing oncoprotein metabolically restricting immunosurveillance [bulk RNA-seq of Atf6 KO DEN/HFD] 6 samples shares immunosurveillance, stress-inducing, activated-atf6, metabolically, oncoprotein, restricting
- GSE255008 A generic drug combination synergizes as exercise enhancers to ameliorate various metabolically-related diseases 28 samples shares metabolically
- GSE303349 CXCL16-driven CD4+ T cells orchestrate immunosurveillance against MHC-I-deficient tumors 24 samples shares immunosurveillance
- GSE277903 Innate tissue immunosurveillance by γδ T cells has real-time dependence on the T cell receptor [RNA-seq] 23 samples shares immunosurveillance
- GSE299638 Tyk2 controls immunosurveillance of colorectal cancer liver metastasis 18 samples shares immunosurveillance
- GSE152067 Adipocyte-specific inactivation of NAMPT, a key NAD+ biosynthetic enzyme, causes a metabolically-unhealthy lean phenotype in female mice during aging 16 samples shares metabolically
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.