Global mapping of H3K27ac and RPB1 occupancy upon WNK463 treatment
ChIP-seq / ATAC-seq (genome binding and open chromatin) · human · 12 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Homo sapiens (human)
- Samples
- 12 samples: 6 conditions, mostly in duplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE244630_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1023927 and SRA study SRP464517. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 12 samples.
How we read this: 6 replicated groups read from 12 sample titles; they account for 12 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7822391 W0Input1 W0Input
- GSM7822392 W0Input2 W0Input
- GSM7822393 W0K271 W0K
- GSM7822394 W0K272 W0K
- GSM7822395 W0Pol1 W0Pol
- GSM7822396 W0Pol2 W0Pol
- GSM7822397 W5Input1 W5Input
- GSM7822398 W5Input2 W5Input
- GSM7822399 W5K271 W5K
- GSM7822400 W5K272 W5K
- GSM7822401 W5Pol1 W5Pol
- GSM7822402 W5Pol2 W5Pol
- GSE244667 Transcriptomics changes upon WNK463 treatment in JJN3 cells 6 samples shares wnk463, treatment, upon
- GSE288469 Genome-wide mapping of H3K27ac by Cut&Tag in CD4+ and CD8+ immune cells of astronauts following prolonged orbital space flight. 36 samples shares h3k27ac, mapping
- GSE246314 Genome-wide profiling of histone modification H3K27ac and CTCF transcription factor binding following VPA treatment in HEK293 cells 18 samples shares h3k27ac, treatment
- GSE300094 Genome binding/occupancy profiling of PHF23 and changes in H3K27ac based on the presence of PHF23 14 samples shares h3k27ac, occupancy
- GSE298628 Genome-wide occupancy of PPARG and RXRA after treatment with PPARG inverse agonist 10 samples shares occupancy, treatment
- GSE38157 The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts 11 samples shares occupancy, global
- GSE193227 Mapping the genomic occupancy by flag-tagged APOBEC3B protein 7 samples shares occupancy, mapping
- GSE239270 Investigate FOXA2, NKX2-1, CTCF and P300 cistrome and enhancer (H3K27ac and H3k4me1) reprogramming during NEPC transformation by ChIP-seq. 104 samples shares h3k27ac
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.