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Genetic rescue of mitochondrial complex I reverses metabolic defects in circadian mutant mice

GSE245850 Mus musculus Expression profiling by high throughput sequencing 15 samples 2026/01/05 GPL30172
Summary
We used single nuclei RNA-seq to compare gene expression from adipocyte circadian mutant mice +/- expression of the yeast NADH dehydrogenase (NDI1). We used RNA-sequencing of fractionated adipocytes from the visceral white adipose tissue of control mice, mice lacking the circadian clock activator Bmal1, and mice lacking the mitochondrial complex I subunit Ndufs2.
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NCBI GEO page ↗ Paper (PMID 41279878) ↗ {# Names what the click gives you. "Open in finder" meant nothing to a visitor who arrived from a search engine and has never seen the tool. #} Find more mouse RNA-seq datasets →
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