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Stimulus-Response signaling dynamics characterize macrophage polarization states

GSE246566 Mus musculus Expression profiling by high throughput sequencing 8 samples Submitted 2024/06/03 Platform GPL13112
Summary
RNAseq data from hMPDMs (HoxB4 myeloid progenitor derived macrophages), BMDMs (bone-marrow derived macrophages), and Raw264.7 cell line in unstimulated condition and 3 hours post LPS stimulation (lipopolysaccharide). Gene expression demonstrates similarities between hMPDMs and BMDMs supporting use of hMPDMs in this study of NFkB stimulus response signaling dynamics, whereas Raw264.7 cells are more distinct from BMDMs in terms of expression LPS-inducible genes.
Published in
Stimulus-response signaling dynamics characterize macrophage polarization states
Singh A, Sen S, Iter M et al. · Cell systems 2024 · PMID 38843840 · doi:10.1016/j.cels.2024.05.002
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Also filed as BioProject PRJNA819468 and SRA study SRP365764. Searching any of these in the dataset finder brings you back here.

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