Effects of Antifibrotic Drugs on Transcriptome of Peripheral Blood Mononuclear Cells in Idiopathic Pulmonary Fibrosis [IPF_PBMC]
RNA-seq (gene expression) · human · 18 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 18 samples: 18 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Effects of Anti-Fibrotic Drugs on Transcriptome of Peripheral Blood Mononuclear Cells in Idiopathic Pulmonary FibrosisInternational journal of molecular sciences · 2024
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE248485_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1044112 and SRA study SRP473749. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 18 sample titles: 18 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7915821 Healthy control [DK22269_01]
- GSM7915822 Healthy control [DK22269_03]
- GSM7915823 Healthy control [DK22269_04]
- GSM7915824 Healthy control [DK22269_14]
- GSM7915825 Healthy control [DK21222_17]
- GSM7915826 Healthy control [DK21222_19]
- GSM7915827 IPF (before PFD) [DK21068_03]
- GSM7915828 IPF (before PFD) [DK22190_01]
- GSM7915829 IPF (before PFD) [DK22190_03]
- GSM7915830 IPF (before NTD) [DK21068_01]
- GSM7915831 IPF (before NTD) [DK22190_05]
- GSM7915832 IPF (before NTD) [DK22190_07]
- GSM7915833 after PFD [DK21068_07]
- GSM7915834 after PFD [DK22190_02]
- GSM7915835 after PFD [DK22190_04]
- GSM7915836 after NTD [DK21068_05]
- GSM7915837 after NTD [DK22190_06]
- GSM7915838 after NTD [DK22190_08]
- GSE310473 Targeting Fused in Sarcoma (FUS): A Novel Antisense Strategy for Treating Idiopathic Pulmonary Fibrosis [RNA-Seq IPF] 16 samples shares ipf, idiopathic, pulmonary, fibrosis
- GSE280114 Bulk RNA-seq data of orbital fibroblasts and peripheral blood mononuclear cells (PBMCs) from thyroid eye disease patients 59 samples shares pbmc, mononuclear, peripheral
- GSE92592 mRNA Sequencing of Ideopathic Pulmonary Fibrosis (IPF) and Control Samples from the Lung Tissue Research Consortium (LTRC) 39 samples shares ipf, pulmonary, fibrosis
- GSE267718 Single cell RNA sequencing (scRNAseq) of urine-derived cells, peripheral blood mononuclear (PBMC), and tumor cells from bladder cancer patients. 33 samples shares pbmc, mononuclear, peripheral
- GSE302368 Effect of hemin on gene expression in erythroid progenitors derived from human sickle cell disease peripheral blood mononuclear cells (PBMC) 30 samples shares pbmc, mononuclear, peripheral
- GSE290026 scRNA and TCR-Seq of peripheral blood mononuclear cells (PBMC) from r/r classical Hodgkin Lymphoma patients under anti-PD1 therapy. 23 samples shares pbmc, mononuclear, peripheral
- GSE277708 Transcriptional profiling of isolated T cells of healthy individuals after treatment with supernatant of peripheral blood mononuclear cells (PBMCs) of the same individuals treated overnight with soluble CD14 (sCD14) 12 samples shares pbmc, mononuclear, peripheral
- GSE327707 Sorted bulk RNA-seq profiling of human peripheral blood mononuclear cell populations across diverse in vitro immune stimuli 150 samples shares mononuclear, peripheral
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.