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Regulation of eNOS by METTL3 in endothelial cells controls blood pressure via RUNX1b

GSE248592 Homo sapiens Expression profiling by high throughput sequencing; Other 14 samples 2024/11/01 GPL20795GPL30209
Summary
As a core subunit of the m6A methyltransferase complex, the downregulation of METTL3 expression in response to Ang II suggests the potential regulation of m6A modification. Our data suggests METTL3 may mediate the dynamic change in m6A landscapes between Ang II with and without overexpression of METTL3.
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