Transcriptomics of PLXDC2 knockdown BMDM treated with PTEN
RNA-seq (gene expression) · mouse · 24 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 24 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Secreted PTEN binds PLXDC2 on macrophages to drive antitumor immunity and tumor suppressionDevelopmental cell · 2024
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE249266_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1048389 and SRA study SRP475666. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 24 more — browse all 24 samples with per-sample file links →
- GSE249265 Transcriptomics of BMDM treated with PTEN in the presence or absence of STAT1 inhibitors 16 samples shares bmdm, pten, treated
- GSE293700 Transcriptome analysis in the prefrontal cortex of PTEN KI heterozygous mice treated with drug 60 samples shares pten, treated
- GSE279654 BMDM from Young and Aged Mice Treated with β-glucan 42 samples shares bmdm, treated
- GSE319618 Prefrontal cortex bulk RNA-seq analysis of drug-treated PTEN KI heterozygous mice at P40 30 samples shares pten, treated
- GSE78849 Investigation of the effect of succinate and dimethyl malonate on murine bone-marrow derived macrophages (BMDMs) treated with or without LPS 21 samples shares bmdm, treated
- GSE196249 Secondary LPS stimulation of BMDMs differentiated from bone marrow of C57B/6J mice treated with 4xLPS, 1xLPS or PBS 18 samples shares bmdm, treated
- GSE250384 Wild type (WT) and Aconitate decarboxylase 1 knockout (Acod1-/-) BMDM treated with Imiquimod for 12h 12 samples shares bmdm, treated
- GSE262892 Effect of lincRNA-p21 knockdown on neonatal mouse cardiomyocytes (CMs) treated with phenylephrine (PE) 12 samples shares knockdown, treated
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.