GEO series
Wild type (WT) and Aconitate decarboxylase 1 knockout (Acod1-/-) BMDM treated with Imiquimod for 12h
GSE250384
Mus musculus
Expression profiling by high throughput sequencing
12 samples
2024/04/17
GPL24247
Summary
The Krebs cycle enzyme Aconitate Decarboxylase 1 (ACOD1) mediates itaconate synthesis in monocytes and macrophages. Here, we explore the role of endogenous ACOD1-itaconate pathway in the activation of BMDM after imiquimod treatment.
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Paper (PMID 38605883) ↗
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