Large-scale bone calluses from skeletally immature and mature mice
RNA-seq (gene expression) · mouse · 44 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 44 samples: 10 conditions, mostly with about 4 replicates eachGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Skeletal Maturity and Age-Related Changes in Immune Cells and Circulatory Factors Impair Large-Scale Bone RegenerationAging cell · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE250201_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1052649 and SRA study SRP478081. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 40 samples.
How we read this: 10 replicated groups read from 44 sample titles; they account for 40 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7975428 Old baseline, replicate 1 Old baseline,
- GSM7975429 Old baseline, replicate 2 Old baseline,
- GSM7975430 Old baseline, replicate 3 Old baseline,
- GSM7975431 Old baseline, replicate 4 Old baseline,
- GSM7975432 Old Day 0 post resection, replicate 1 Old Day 0 post resectio…
- GSM7975433 Old Day 0 post resection, replicate 2 Old Day 0 post resectio…
- GSM7975434 Old Day 0 post resection, replicate 3 Old Day 0 post resectio…
- GSM7975435 Old Day 0 post resection, replicate 4 Old Day 0 post resectio…
- GSM7975436 Old Day 14 post resection, replicate 1 Old Day 14 post resecti…
- GSM7975437 Old Day 14 post resection, replicate 2 Old Day 14 post resecti…
- GSM7975438 Old Day 14 post resection, replicate 3 Old Day 14 post resecti…
- GSM7975439 Old Day 14 post resection, replicate 4 Old Day 14 post resecti…
- GSM7975440 Old Day 2 post resection, replicate 1 Old Day 2 post resectio…
- GSM7975441 Old Day 2 post resection, replicate 2 Old Day 2 post resectio…
- GSM7975442 Old Day 2 post resection, replicate 3 Old Day 2 post resectio…
- GSM7975443 Old Day 2 post resection, replicate 4 Old Day 2 post resectio…
- GSM7975444 Old Day 5 post resection, replicate 1 Old Day 5 post resectio…
- GSM7975445 Old Day 5 post resection, replicate 2 Old Day 5 post resectio…
- GSM7975446 Old Day 5 post resection, replicate 3 Old Day 5 post resectio…
- GSM7975447 Old Day 5 post resection, replicate 4 Old Day 5 post resectio…
- GSM7975448 Young baseline, replicate 2 Young baseline,
- GSM7975449 Young baseline, replicate 3 Young baseline,
- GSM7975450 Young baseline, replicate 4 Young baseline,
- GSM7975451 Young baseline, replicate 6 Young baseline,
- GSM7975452 Young Day 0 post resection, replicate 1 Young Day 0 post resect…
- GSM7975453 Young Day 0 post resection, replicate 2 Young Day 0 post resect…
- GSM7975454 Young Day 0 post resection, replicate 3 Young Day 0 post resect…
- GSM7975455 Young Day 0 post resection, replicate 4 Young Day 0 post resect…
- GSM7975456 Young Day 14 post resection, replicate 1 Young Day 14 post resec…
- GSM7975457 Young Day 14 post resection, replicate 2 Young Day 14 post resec…
- GSM7975458 Young Day 14 post resection, replicate 3 Young Day 14 post resec…
- GSM7975459 Young Day 14 post resection, replicate 4 Young Day 14 post resec…
- GSM7975460 Young Day 2 post resection, replicate 1 Young Day 2 post resect…
- GSM7975461 Young Day 2 post resection, replicate 2 Young Day 2 post resect…
- GSM7975462 Young Day 2 post resection, replicate 3 Young Day 2 post resect…
- GSM7975463 Young Day 2 post resection, replicate 4 Young Day 2 post resect…
- GSM7975464 Young Day 5 post resection, replicate 2 Young Day 5 post resect…
- GSM7975465 Young Day 5 post resection, replicate 3 Young Day 5 post resect…
- GSM7975466 Young Day 5 post resection, replicate 4 Young Day 5 post resect…
- GSM7975467 Young Day 5 post resection, replicate 5 Young Day 5 post resect…
+ 4 more — browse all 44 samples with per-sample file links →
- GSE250199 Bulk RNA-seq data of large-scale bone calluses from skeletally immature and mature mice 40 samples shares large-scale, skeletally, calluses, immature, mature, bone
- GSE250200 Single-cell RNA-seq data of large-scale bone calluses from skeletally immature and mature mice 4 samples shares large-scale, skeletally, calluses, immature, mature, bone
- GSE295537 Chil3+ immature neutrophils inhibit anti-tumor immunity and impede immune checkpoint blockade therapy in bone metastases [RNA-Seq] 6 samples shares immature, mature, bone
- GSE295533 Chil3+ immature neutrophils inhibit anti-tumor immunity and impede immune checkpoint blockade therapy in bone metastases [scRNA-seq] 2 samples shares immature, mature, bone
- GSE218858 Hyperactive STAT5 Hijacks T-Cell Receptor Signaling and Drives Immature T-Cell Acute Lymphoblastic Leukemia 51 samples shares immature, mature
- GSE273779 Effect of Col1a2 mutation in the gene expression of immature and mature osteoblasts in a mouse model of osteognesis imperfecta (OI) 14 samples shares immature, mature
- GSE272525 Early life stress modulates neonatal somatosensation and the transcriptional profile of immature sensory neurons 12 samples shares immature, mature
- GSE302721 Allopregnanolone is neuroprotective in hypoxic-ischemic injury of the immature brain 10 samples shares immature, mature
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.