Allopregnanolone is neuroprotective in hypoxic-ischemic injury of the immature brain
RNA-seq (gene expression) · mouse · 10 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 10 samples: 10 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE302721_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1290410 and SRA study SRP600260. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 10 sample titles: 10 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9110190 RNA seq mouse 1_Hypoxia Ischemia Whole Brain
- GSM9110191 RNA seq Mouse 2_Hypoxia Ischemia whole Brain
- GSM9110192 RNA seq Mouse 3_Hypoxia Ischemia whole Brain
- GSM9110193 RNA seq Mouse 4_Hypoxia Ischemia whole Brain
- GSM9110194 RNA seq Mouse 5_Hypoxia Ischemia Whole brain
- GSM9110195 RNA seq Mouse 6_Allo treated Hypoxia Ischemia whole brain
- GSM9110196 RNA seq Mouse 7_Allo treated Hypoxia Ischemia whole brain
- GSM9110197 RNA seq Mouse 8_Allo treated Hypoxia Ischemia whole brain
- GSM9110198 RNA seq Mouse 9_Allo treated Hypoxia Ischemia whole brain
- GSM9110199 RNA seq Mouse 10_Allo treated Hypoxia Ischemia whole brain
- GSE249085 TSG-6 mediated extracellular matrix modifications regulate hypoxic-ischemic brain injury 20 samples shares hypoxic-ischemic, injury, brain
- GSE312452 MicroRNA210 regulated brain pericyte dysfunction exacerbates hypoxic-ischemic brain injury in neonatal mice 15 samples shares hypoxic-ischemic, injury, brain
- GSE325742 Timing-dependent neuroprotection of dexamethasone in neonatal hypoxic-ischemic brain injury mouse model : Transcriptomic insights into synaptic signaling and calcium homeostasis 15 samples shares hypoxic-ischemic, injury, brain
- GSE235618 Effect of a dendritic cells derived extracellular vesicle as therapeutic vaccine platform to induce neuroprotective immunity for spinal cord injury 21 samples shares neuroprotective, injury
- GSE313801 Artificial intelligence-assisted prediction of PANoptosis related molecular targets and precise screening of neuroprotective drugs for spinal cord injury 9 samples shares neuroprotective, injury
- GSE306583 Developmental trajectory of the mouse transcriptome following placental allopregnanolone insufficiency in the somatosensosry cortex, hippocampus and cerebellum 175 samples shares allopregnanolone
- GSE218858 Hyperactive STAT5 Hijacks T-Cell Receptor Signaling and Drives Immature T-Cell Acute Lymphoblastic Leukemia 51 samples shares immature
- GSE250201 Large-scale bone calluses from skeletally immature and mature mice 44 samples shares immature
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.