Cpt1a drives lipid remodeling in primed-to-naïve pluripotency transition [RNA-Seq 1]
RNA-seq (gene expression) · mouse · 18 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 18 samples: 6 conditions, mostly in triplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Cpt1a Drives primed-to-naïve pluripotency transition through lipid remodelingCommunications biology · 2024
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE252224_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1058625 and SRA study SRP480533. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 18 samples.
How we read this: 6 replicated groups read from 18 sample titles; they account for 18 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7997775 ESC_1 ESC
- GSM7997776 ESC_2 ESC
- GSM7997777 ESC_3 ESC
- GSM7997778 EpiSC_1 EpiSC
- GSM7997779 EpiSC_2 EpiSC
- GSM7997780 EpiSC_3 EpiSC
- GSM7997781 rES_1 rES
- GSM7997782 rES_2 rES
- GSM7997783 rES_3 rES
- GSM7997784 D3_1 D3
- GSM7997785 D3_2 D3
- GSM7997786 D3_3 D3
- GSM7997787 D5_1 D5
- GSM7997788 D5_2 D5
- GSM7997789 D5_3 D5
- GSM7997790 D8_1 D8
- GSM7997791 D8_2 D8
- GSM7997792 D8_3 D8
- GSE253147 Cpt1a drives lipid remodeling in primed-to-naïve pluripotency transition 33 samples shares cpt1a, primed-to-na, pluripotency, remodeling, transition, drives, lipid
- GSE274492 The remodeling of bivalent chromatin is essential for mouse peri-implantation embryogenesis [Valid RNA-Seq] 200 samples shares remodeling, rna-seq
- GSE259380 TG6050, an oncolytic vaccinia virus encoding interleukin-12 and anti-CTLA-4 antibody induces tumor regression through profound tumor microenvironment remodeling and strong antitumor adaptive immune response [RNA-seq] 149 samples shares remodeling, rna-seq
- GSE313258 Metabolite-driven remodeling of hepatic lipid metabolism by the plasticizer di-isononyl phthalate 54 samples shares remodeling, lipid
- GSE253848 Mechano-oncogenic cytoskeletal remodeling drives leukemic transformation with mitochondrial vesicle-mediated STING activation 54 samples shares remodeling, drives
- GSE299114 Endothelial Cells retain inflammatory memory through chromatin remodeling [RNA-Seq 2] 53 samples shares remodeling, rna-seq
- GSE282766 VEGFA Stop-gained Variant Deteriorates Cardiac Remodeling in Myocardial Infarction [RNA-seq] 43 samples shares remodeling, rna-seq
- GSE292815 Diet-induced phospholipid remodeling dictates ferroptosis sensitivity and tumorigenesis in the pancreas 39 samples shares remodeling, lipid
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.