← BioTransfer GEO Dataset Finder
GEO series

Spatial multi-omics in skeletal muscle unravel complex myofiber architecture

GSE253441 Mus musculus Expression profiling by high throughput sequencing 4 samples Submitted 2024/09/19 Platform GPL19057
Summary
Skeletal muscles are complex organs consisting of multiple tissues, including connective tissue, blood vessels, nerves and multinucleated myofibers. Single-nucleus transcriptomics analyses have revealed distinctive myonuclear populations related to myofiber type and to specialized regions, including neuromuscular and myotendinous junctions. However, the use of tissue dissociation methods prevented access to global spatial organization. Here we applied RNA tomography (TOMOseq), a spatial transcriptomics approach, to explore gene expression differences along murine tibialis anterior muscles.
Published in
Spatial multi-omics in whole skeletal muscle reveals complex tissue architecture
Martínez Mir C, Pisterzi P, De Poorter I et al. · Communications biology 2024 · PMID 39369093 · doi:10.1038/s42003-024-06949-1
This dataset
Download

Direct links to NCBI, no account and no request form: the whole study as GSE253441_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 4 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1065811 and SRA study SRP484172. Searching any of these in the dataset finder brings you back here.

Samples in this study

The sample list for this study is not cached yet. Press Sort into groups and it will be fetched from NCBI.

+ 4 more — browse all 4 samples with per-sample file links →

Similar datasets

Search all mouse RNA-seq datasets in GEO →

Share this dataset

Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.