Interuption of Klf5 acetylaiton at K358 affects gene expression profiles in Pten deficient mouse prostates
RNA-seq (gene expression) · mouse · 20 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 20 samples: 20 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Interruption of KLF5 acetylation promotes PTEN-deficient prostate cancer progression by reprogramming cancer-associated fibroblastsThe Journal of clinical investigation · 2024
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE253523_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1066205 and SRA study SRP484391. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 20 sample titles: 20 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8022541 KRKR_5759_AP
- GSM8022542 KRKR_5760_AP
- GSM8022543 KRKR_5762_AP
- GSM8022544 KRKR_5763_AP
- GSM8022545 KRW_5696_AP
- GSM8022546 KRW_5764_AP
- GSM8022547 KRW_5816_AP
- GSM8022548 WW_5705_AP
- GSM8022549 WW_5831_AP
- GSM8022550 WW_5834_AP
- GSM8022551 KRKR_5759_DP
- GSM8022552 KRKR_5760_DP
- GSM8022553 KRKR_5762_DP
- GSM8022554 KRKR_5763_DP
- GSM8022555 KRW_5696_DP
- GSM8022556 KRW_5764_DP
- GSM8022557 KRW_5816_DP
- GSM8022558 WW_5705_DP
- GSM8022559 WW_5831_DP
- GSM8022560 WW_5834_DP
- GSE262893 Interuption of Klf5 acetylaiton at K358 affects tumor microenvironment in Pten deficient mouse prostates 4 samples shares klf5, k358, interuption, acetylaiton, deficient, prostates, affects
- GSE269422 Single-Cell Sequencing Analysis of KLF5-Induced Multilineage Reprogramming in EpiSCs 16 samples shares klf5
- GSE145420 RNA-seq on in vitro 3D structure of Klf5-KO biliary epithelial cells 15 samples shares klf5
- GSE281940 Role of KLF5 in Ischemia Reperfusion Injury 12 samples shares klf5
- GSE263578 scRNA-seq for Klf5 or SE deletion of mESC differentiation 4 samples shares klf5
- GSE9535 Identifying targets of Klf2, Klf4, Klf5 and p53 in mouse embryonic stem cells 33 samples shares klf5
- GSE281941 Klf5 functions as a multi-lineage reprogramming transcription factor 30 samples shares klf5
- GSE309196 Ythdc1-p300-Klf5 complex-mediated Golgi dysfunction promotes aortic aneurysm 2 samples shares klf5
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.