GEO series
Effects of Palovarotene on Ext1-deficient and wild type cultured mouse chondrocytes
GSE254042
Mus musculus
Expression profiling by high throughput sequencing
12 samples
2024/08/02
GPL24247
Summary
Palovarotene, the agonist of the retionic acid nuclear receptor gamma has been shonw to inhibit osteochondroma formation in the mouse osteochondroma models. To understand the biological cation of Palovarotene, the transcriptome analysis was performed using 3D chondrocyte cultures Compaison of Palovarotene-treated groups with vehicle control groups demonstrated the gene lists and biological pathway modulated by Palovarotene-activated retionic acid receptor signaling pathways.
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Paper (PMID 39062860) ↗
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