Vascular dysfunction is the primary cause of symptom onset in a mouse model of oxaliplatin-induced peripheral neuropathy: comparison of gene expression in mice injected with Oxaliplatine or control solution [BHN-OXA_A2020]
RNA-seq (gene expression) · mouse · 24 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 24 samples: 24 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Vascular dysfunction is at the onset of oxaliplatin-induced peripheral neuropathy symptoms in miceLife science alliance · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE255097_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1073509 and SRA study SRP488226. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 24 sample titles: 24 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8064062 Sample sham1 technical replicate a
- GSM8064063 Sample sham1 technical replicate b
- GSM8064064 Sample sham1 technical replicate c
- GSM8064065 Sample sham1 technical replicate d
- GSM8064066 Sample sham2 technical replicate a
- GSM8064067 Sample sham2 technical replicate b
- GSM8064068 Sample sham2 technical replicate c
- GSM8064069 Sample sham2 technical replicate d
- GSM8064070 Sample sham3 technical replicate a
- GSM8064071 Sample sham3 technical replicate b
- GSM8064072 Sample sham3 technical replicate c
- GSM8064073 Sample sham3 technical replicate d
- GSM8064074 Sample oxa1 technical replicate a
- GSM8064075 Sample oxa1 technical replicate b
- GSM8064076 Sample oxa1 technical replicate c
- GSM8064077 Sample oxa1 technical replicate d
- GSM8064078 Sample oxa2 technical replicate a
- GSM8064079 Sample oxa2 technical replicate b
- GSM8064080 Sample oxa2 technical replicate c
- GSM8064081 Sample oxa2 technical replicate d
- GSM8064082 Sample oxa3 technical replicate a
- GSM8064083 Sample oxa3 technical replicate b
- GSM8064084 Sample oxa3 technical replicate c
- GSM8064085 Sample oxa3 technical replicate d
- GSE255096 Vascular dysfunction is the primary cause of symptom onset in a mouse model of oxaliplatin-induced peripheral neuropathy: comparison of gene expression in blood vessels from mouse brain and sciatic nerves [BHE-BHN_A2017] 24 samples shares oxaliplatin-induced, dysfunction, peripheral, neuropathy, comparison
- GSE284085 The extracellular matrix drives guanylate production and protects pancreatic cancer cells from oxaliplatin-induced DNA damage. 12 samples shares oxaliplatin-induced
- GSE233805 Oxaliplatin-induced cardiotoxicity in mice is connected to the changes in energy metabolism in the heart tissue 9 samples shares oxaliplatin-induced
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.