The lectin Siglec-G functions as an inhibitory receptor in CD8+ T cell and can be targeted to enhance therapeutic antitumor immunity.
Direct links to NCBI, no account and no request form: the whole study as GSE255336_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 6 samples. Raw sequencing reads are also available from ENA.
Also filed as BioProject PRJNA1074707 and SRA study SRP488948. Searching any of these in the dataset finder brings you back here.
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+ 6 more — browse all 6 samples with per-sample file links →
- GSE272424 Rejuvenating endogenous antitumor immunity via a chimeric receptor-engineered oncolytic virus targeting tumor-associated macrophages 6 samples
- GSE278990 Single-cell screens identify ADAM12 as a fibroblast checkpoint impeding anti-tumor immunity 73 samples
- GSE306262 Astrocyte glucocorticoid receptor signaling restricts neuronal plasticity [RNA-seq] 40 samples
- GSE322551 Engineered bacteria as exogenous organelle mimics restore PTEN and p53 tumor suppressor functions for cancer therapy 30 samples
- GSE333587 Formylpeptide Receptor Activation Attenuates Renovascular Remodeling in Neurogenic Hypertension (Kidney) 19 samples
- GSE281001 The C3-C3aR axis modulates trained immunity in alveolar macrophages 8 samples
- GSE314817 Multi-tissue, multi-time-point transcriptomic atlas of aging in mice and rats [mouse] 2432 samples
- GSE293709 Transcriptome analysis in the prefrontal cortex of different ASD mouse models treated with drug 1565 samples
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