Germline-like TCR alpha chains shared between autoreactive T cells in blood and pancreas [dataset2]
RNA-seq (gene expression) · human · 1625 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 1625 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Germline-like TCR-α chains shared between autoreactive T cells in blood and pancreasNature communications · 2024
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE256479_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1079762 and SRA study SRP491408. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 1625 more — browse all 1625 samples with per-sample file links →
- GSE256481 Germline-like TCR alpha chains shared between autoreactive T cells in blood and pancreas 2424 samples shares tcr, germline-like, autoreactive, pancreas, chains, shared, alpha
- GSE255400 Germline-like TCR alpha chains shared between autoreactive T cells in blood and pancreas [dataset1] 799 samples shares tcr, germline-like, autoreactive, pancreas, chains, shared, alpha
- GSE243905 Single-cell TCR profiling of CSF and blood cells of PWH reveals persistent and shared infected T cell clones across tissue compartments even after ART 82 samples shares tcr, shared
- GSE315928 Differential T cell clonal dynamics underlie outcomes to frontline chemoimmunotherapy in advanced gastric cancer [paired scRNA/TCR-seq] 94 samples shares tcr
- GSE284664 RESET: A reversible TCR-coupled antigen receptor with superior targeting sensitivity and pharmacologically controlled anti-tumor activity 62 samples shares tcr
- GSE305714 TCR signaling via NFATc1 constrains IL-15-induced NK-like activation of human memory CD8+ T cells [RNAseq_CD3_48H] 40 samples shares tcr
- GSE305712 TCR signaling via NFATc1 constrains IL-15-induced NK-like activation of human memory CD8+ T cells [RNAseq_IONO_12H] 40 samples shares tcr
- GSE167036 Single cell profiling of primary and paired metastatic lymph node tumors in breast cancer patients(10x RNA and TCR) 32 samples shares tcr
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.