Germline-like TCR alpha chains shared between autoreactive T cells in blood and pancreas
RNA-seq (gene expression) · human · 2424 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 2424 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Germline-like TCR-α chains shared between autoreactive T cells in blood and pancreasNature communications · 2024
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE256481_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1079752 and SRA study SRP489013. Searching any of these in the dataset finder brings you back here.
The grouping that defines any comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Sample titles run lib52657 … lib53991 and carry no group information.
- GSM8071218 lib52657
- GSM8071219 lib52658
- GSM8071220 lib52659
- GSM8071221 lib52660
- GSM8071222 lib52661
- GSM8071223 lib52662
- GSM8071224 lib52663
- GSM8071225 lib52664
- GSM8071226 lib52665
- GSM8071227 lib52666
- GSM8071228 lib52667
- GSM8071229 lib52668
- GSM8071230 lib52669
- GSM8071231 lib52670
- GSM8071232 lib52671
- GSM8071233 lib52672
- GSM8071234 lib52673
- GSM8071235 lib52674
- GSM8071236 lib52675
- GSM8071237 lib52676
- GSM8071238 lib52677
- GSM8071239 lib52678
- GSM8071240 lib52679
- GSM8071241 lib52680
- GSM8071242 lib52681
- GSM8071243 lib52682
- GSM8071244 lib52683
- GSM8071245 lib52684
- GSM8071246 lib52685
- GSM8071247 lib52686
- GSM8071248 lib52687
- GSM8071249 lib52688
- GSM8071250 lib52689
- GSM8071251 lib52749
- GSM8071252 lib52750
- GSM8071253 lib52751
- GSM8071254 lib52752
- GSM8071255 lib52753
- GSM8071256 lib52754
- GSM8071257 lib52755
+ 2384 more — browse all 2424 samples with per-sample file links →
- GSE256479 Germline-like TCR alpha chains shared between autoreactive T cells in blood and pancreas [dataset2] 1625 samples shares tcr, germline-like, autoreactive, pancreas, chains, shared, alpha, blood
- GSE255400 Germline-like TCR alpha chains shared between autoreactive T cells in blood and pancreas [dataset1] 799 samples shares tcr, germline-like, autoreactive, pancreas, chains, shared, alpha, blood
- GSE243905 Single-cell TCR profiling of CSF and blood cells of PWH reveals persistent and shared infected T cell clones across tissue compartments even after ART 82 samples shares tcr, shared, blood
- GSE298690 Integrated transcriptome and single-cell sequencing analysis identify blood-pancreas shared lncRNA biomarkers in new-onset T2DM 16 samples shares pancreas, shared, blood
- GSE290026 scRNA and TCR-Seq of peripheral blood mononuclear cells (PBMC) from r/r classical Hodgkin Lymphoma patients under anti-PD1 therapy. 23 samples shares tcr, blood
- GSE296771 TCR-stimulation of peripheral-blood CD8+ T cells. 16 samples shares tcr, blood
- GSE304309 Single-cell transcriptomic and TCR profiling of peripheral double-positive T cells in healthy human blood [scRNA-seq] 8 samples shares tcr, blood
- GSE281005 Adaptive Biotechnologies TCRbeta sequencing of 174 primary and 42 metastatic pancreatic ductal adenocarcinoma tumor samples from FFPE curls and 215 matched blood plus 73 additional blood samples 505 samples shares tcr, blood
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.