The effect of RVG-SCMH1-Evs treatment on photothrombotic (PT) stroke mice
RNA-seq (gene expression) · mouse · 12 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 12 samples: 3 × Mouse,Sham-Vector, vs 3 × Mouse,Sham-circSCMH1, vs 3 × Mouse,PT-Vector, vs 3 × Mouse,PT-circSCMH1,Groups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Circular RNA SCMH1 suppresses KMO expression to inhibit mitophagy and promote functional recovery following strokeTheranostics · 2024
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE261613_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1088110 and SRA study SRP495283. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 12 samples.
How we read this: 4 replicated groups read from 12 sample titles; they account for 12 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8147453 Mouse,Sham-Vector,rep1 Mouse,Sham-Vector,
- GSM8147454 Mouse,Sham-Vector,rep2 Mouse,Sham-Vector,
- GSM8147455 Mouse,Sham-Vector,rep3 Mouse,Sham-Vector,
- GSM8147456 Mouse,Sham-circSCMH1,rep1 Mouse,Sham-circSCMH1,
- GSM8147457 Mouse,Sham-circSCMH1,rep2 Mouse,Sham-circSCMH1,
- GSM8147458 Mouse,Sham-circSCMH1,rep3 Mouse,Sham-circSCMH1,
- GSM8147459 Mouse,PT-Vector,rep1 Mouse,PT-Vector,
- GSM8147460 Mouse,PT-Vector,rep2 Mouse,PT-Vector,
- GSM8147461 Mouse,PT-Vector,rep3 Mouse,PT-Vector,
- GSM8147462 Mouse,PT-circSCMH1,rep1 Mouse,PT-circSCMH1,
- GSM8147463 Mouse,PT-circSCMH1,rep2 Mouse,PT-circSCMH1,
- GSM8147464 Mouse,PT-circSCMH1,rep3 Mouse,PT-circSCMH1,
- GSE133897 Transcriptomic and proteomic multi-model global gene expression analysis reveals regulatory signatures during ischemia stroke (photothrombotic cerebral ischemia stroke) 18 samples shares photothrombotic, stroke
- GSE261670 ASOs are an effective treatment for disease-associated oligodendrocyte signatures in premanifest and symptomatic SCA3 mice 74 samples shares treatment
- GSE249630 Modeling T cell temporal response to cancer immunotherapy rationalize development of combinatorial treatments protocols 1372 samples shares treatment
- GSE269328 Glucagon receptor agonism and treatment withdrawal effect on liver transcriptomes of diet-induced obese mice 24 samples shares treatment
- GSE261792 Effect of Ethoxysanguinarine treatment on gene expression after Angiotensin-II infused C57BL/6 mice 18 samples shares treatment
- GSE265949 Effect of endothelial YAP/TAZ on neuroinflammation and outcome after ischemic stroke in mice 16 samples shares stroke
- GSE294630 CDA HFD mice analysed for hepatic gene expression after treatment with semaglutide 97 samples shares treatment
- GSE338091 Effect of semaglutide treatment in aged mice 10 samples shares treatment
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.