H3K27 dimethylation dynamics reveal stepwise establishment of facultative heterochromatin in early mouse embryos [RNA-Seq]
DNA methylation · mouse · 10 samples
- What it is
- DNA methylationChemical marks on DNA that help switch genes on or off.
- Organism
- Mus musculus (mouse)
- Samples
- 10 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- H3K27 dimethylation dynamics reveal stepwise establishment of facultative heterochromatin in early mouse embryosNature cell biology · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE263441_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for beta-value tables or raw IDAT files among the supplementary files.
Also filed as BioProject PRJNA1097552 and SRA study SRP500362. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 10 more — browse all 10 samples with per-sample file links →
- GSE264193 H3K27 dimethylation dynamics reveal stepwise establishment of facultative heterochromatin in early mouse embryos [ChIP-seq] 57 samples shares h3k27, heterochromatin, dimethylation, establishment, facultative, dynamics, stepwise, embryos
- GSE73952 Distinct features in establishing H3K4me3 and H3K27me3 in pre-implantation embryos 67 samples shares h3k27, embryos
- GSE287032 H3K27me3 and the PRC1-H2AK119ub pathway cooperatively maintain heterochromatin and transcriptional silencing after the loss of H3K9 methylation [ChIP-seq] 20 samples shares h3k27, heterochromatin
- GSE206179 Stepwise de novo establishment of inactive X chromosome architecture in early development [XEN cells RNA-seq] 32 samples shares establishment, stepwise
- GSE206011 Stepwise de novo establishment of inactive X chromosome architecture in early development 262 samples shares establishment, stepwise
- GSE244496 Establishment of nuclear organization in mouse embryos is regulated by multiple and redundant epigenetic pathways. 183 samples shares establishment, embryos
- GSE318279 Self-clustering of three CBX2 molecules drives PRC2 to promote facultative heterochromatinization of Polycomb target genes 33 samples shares heterochromatin, facultative
- GSE206180 Stepwise de novo establishment of inactive X chromosome architecture in early development [XEN cells ChIP-seq] 20 samples shares establishment, stepwise
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.