Leveraging Integrated RNA Sequencing to Decipher Adrenomedullin’s Protective Mechanisms in Experimental Bronchopulmonary Dysplasia
Single-cell RNA-seq · mouse · 12 samples
- What it is
- Single-cell RNA-seqGene activity measured in thousands of individual cells, so cell types can be told apart. Read from the summary: GEO's own type field only says 'expression profiling by sequencing', so confirm it in the paper.
- Organism
- Mus musculus (mouse)
- Samples
- 12 samples: 12 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Leveraging Integrated RNA Sequencing to Decipher Adrenomedullin's Protective Mechanisms in Experimental Bronchopulmonary DysplasiaGenes · 2024
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE264612_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Single-cell studies usually ship their counts as 10x files (matrix.mtx, barcodes.tsv, features.tsv), an .h5 file, or an .rds / .h5ad object that Seurat or Scanpy can open. Look for those among the supplementary files.
Also filed as BioProject PRJNA1103240 and SRA study SRP503419. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 12 sample titles: 12 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8223894 VH-01_S32_AMKO-LPS
- GSM8223895 VH-02_S33_AMKO-LPS
- GSM8223896 VH-03_S34_WT-PBS
- GSM8223897 VH-04_S35_WT-PBS
- GSM8223898 VH-05_S36_WT-PBS
- GSM8223899 VH-06_S37_AMKO-PBS
- GSM8223900 VH-07_S38_AMKO-PBS
- GSM8223901 VH-08_S39_AMKO-PBS
- GSM8223902 VH-09_S40_WT-LPS
- GSM8223903 VH-10_S41_WT-LPS
- GSM8223904 VH-11_S42_WT-LPS
- GSM8223905 VH-12_S43_AMKO-LPS
- GSE276601 Molecular mechanisms of the Xiao-chai-hu-tang on chronic stress-induced colorectal cancer growth based on an integrated network pharmacology and RNA sequencing approach with experimental validation 12 samples shares experimental, integrated
- GSE271362 CGRP-Related Neuropeptide Adrenomedullin 2 Promotes Tissue-Protective ILC2 Responses and Limits Intestinal Inflammation 11 samples shares adrenomedullin, protective
- GSE262215 NR4A1 Mediates Offspring Bronchopulmonary Dysplasia-Like Lung Injury Induced by Intrauterine Inflammation in Mice 6 samples shares bronchopulmonary, dysplasia
- GSE181497 High-mobility group box1 peptide ameliorates bronchopulmonary dysplasia (BPD) via suppressing inflammation and fibrosis in a mouse model. 3 samples shares bronchopulmonary, dysplasia
- GSE302715 A tumor-associated macrophage-targeted immunocytokine leveraging T and NK cell synergy for potent cancer immunotherapy [scRNA-seq] 187 samples shares leveraging
- GSE227937 MicroRNA-150 controls experimental autoimmune encephalomyelitis by regulating CD4 T cell differentiation and function 69 samples shares experimental
- GSE272981 BAT and SAT Treg cells and of BAT tissue with or without Treg cells under different experimental conditions 62 samples shares experimental
- GSE271779 BAT and SAT Treg cells and of BAT tissue with or without Treg cells under different experimental conditions [RNA-seq] 60 samples shares experimental
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.