A Fast Chemical Reprogramming System to Generate Human Pluripotent Stem Cells [RNA-seq]
RNA-seq (gene expression) · human · 31 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 31 samples: 31 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- A rapid chemical reprogramming system to generate human pluripotent stem cellsNature chemical biology · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE264658_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1103754 and SRA study SRP503580. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 31 sample titles: 31 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8224832 hADSCs-1013,RNA-seq
- GSM8224833 hCiPSCs-0618-1#,RNA-seq
- GSM8224834 hCiPSCs-0618-2#,RNA-seq
- GSM8224835 hCiPSCs-1013-A#,RNA-seq
- GSM8224836 hCiPSCs-1013-D#,RNA-seq
- GSM8224837 SID6-1013-V4_rep1,RNA-seq
- GSM8224838 SID6-1013-V4_rep2,RNA-seq
- GSM8224839 SID6-1013-V4-WA4_rep1,RNA-seq
- GSM8224840 SID6-1013-V4-WA4_rep2,RNA-seq
- GSM8224841 hADSCs-0509_rep1,RNA-seq
- GSM8224842 hADSCs-0509_rep2,RNA-seq
- GSM8224843 hADSCs-0809_rep1,RNA-seq
- GSM8224844 hADSCs-0809_rep2,RNA-seq
- GSM8224845 hADSCs-1003_rep1,RNA-seq
- GSM8224846 hADSCs-1013_rep1,RNA-seq
- GSM8224847 hADSCs-1013_rep2,RNA-seq
- GSM8224848 hADSCs-1217_rep1,RNA-seq
- GSM8224849 hADSCs-1217_rep2,RNA-seq
- GSM8224850 hADSCs-0605_rep1,RNA-seq
- GSM8224851 hADSCs-0618_rep1,RNA-seq
- GSM8224852 hADSCs-0618_rep2,RNA-seq
- GSM8224853 H1,RNA-seq
- GSM8224854 H9,RNA-seq
- GSM8596541 S1D0.5,scRNA-seq
- GSM8596542 S1D4,scRNA-seq
- GSM8596543 S1D6,scRNA-seq
- GSM8596544 S2D2,scRNA-seq
- GSM8596545 S2D4,scRNA-seq
- GSM8596546 S3D3,scRNA-seq
- GSM8596547 S3D6,scRNA-seq
- GSM8596548 S3D10,scRNA-seq
- GSE226477 Bulk RNA-seq of neuromuscular system models generated from human induced pluripotent stem cells (hiPSCs) 15 samples shares pluripotent, generate, rna-seq, system, stem
- GSE262419 Informing Hazard Identification and Risk Characterization of Environmental Chemicals by Combining Transcriptomic and Functional Data from Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes 4558 samples shares pluripotent, chemical, stem
- GSE274217 METTL3-dependent m6A RNA methylation represses transposable elements derived enhancers to suppress naïve pluripotency in human pluripotent stem cells [RNA-Seq] 28 samples shares pluripotent, rna-seq, stem
- GSE283776 Human stem cell-derived GABAergic interneuron development reveals early emergence of subtype diversity followed by gradual electrochemical maturation [snRNA-seq] 19 samples shares chemical, rna-seq, stem
- GSE342790 Development-inspired approach for the derivation of functional and transplantable salivary gland organoids from human pluripotent stem cells [RNA-Seq] 16 samples shares pluripotent, rna-seq, stem
- GSE282387 Temozolomide Induces Glioblastoma Dedifferentiation into Highly Malignant Stem-like Cells Through Senescence-Associated Reprogramming via HIF1α/HIF2α Regulation [RNA-seq] 12 samples shares reprogramming, rna-seq, stem
- GSE287227 Transient SP140 inhibition unlocks hematopoietic stem cell fate from human pluripotent stem cells [scRNA-seq] 9 samples shares pluripotent, rna-seq, stem
- GSE226482 Single cell RNA sequencing of spinal motor neurons and interneurons differentiated from isogenic FUS and TARDBP human induced pluripotent stem cell lines harbouring ALS-causative mutations 1415 samples shares pluripotent, stem
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.