Plasticity and lineage commitment of individual Th1 cells are determined by stable T-bet expression quantities (ChIP-Seq)
ChIP-seq / ATAC-seq (genome binding and open chromatin) · mouse · 84 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Mus musculus (mouse)
- Samples
- 84 samples: 42 conditions, mostly in duplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Plasticity and lineage commitment of individual T(H)1 cells are determined by stable T-bet expression quantitiesScience advances · 2024
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE266175_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1106057 and SRA study SRP504778. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 84 samples.
How we read this: 42 replicated groups read from 84 sample titles; they account for 84 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8241858 Het_Neutral_Input_R1 Het_Neutral_Input
- GSM8241859 Het_Neutral_Input_R2 Het_Neutral_Input
- GSM8241860 Het_Neutral_K27ac_R1 Het_Neutral_K27ac
- GSM8241861 Het_Neutral_K27ac_R2 Het_Neutral_K27ac
- GSM8241862 Het_Neutral_K27me3_R1 Het_Neutral_K27me3
- GSM8241863 Het_Neutral_K27me3_R2 Het_Neutral_K27me3
- GSM8241864 Het_Neutral_K4me1_R1 Het_Neutral_K4me1
- GSM8241865 Het_Neutral_K4me1_R2 Het_Neutral_K4me1
- GSM8241866 Het_Neutral_K4me3_R1 Het_Neutral_K4me3
- GSM8241867 Het_Neutral_K4me3_R2 Het_Neutral_K4me3
- GSM8241868 Het_Neutral_K9me3_R1 Het_Neutral_K9me3
- GSM8241869 Het_Neutral_K9me3_R2 Het_Neutral_K9me3
- GSM8241870 Het_Th2_Input_R1 Het_Th2_Input
- GSM8241871 Het_Th2_Input_R2 Het_Th2_Input
- GSM8241872 Het_Th2_K27ac_R1 Het_Th2_K27ac
- GSM8241873 Het_Th2_K27ac_R2 Het_Th2_K27ac
- GSM8241874 Het_Th2_K27me3_R1 Het_Th2_K27me3
- GSM8241875 Het_Th2_K27me3_R2 Het_Th2_K27me3
- GSM8241876 Het_Th2_K4me1_R1 Het_Th2_K4me1
- GSM8241877 Het_Th2_K4me1_R2 Het_Th2_K4me1
- GSM8241878 Het_Th2_K4me3_R1 Het_Th2_K4me3
- GSM8241879 Het_Th2_K4me3_R2 Het_Th2_K4me3
- GSM8241880 Het_Th2_K9me3_R1 Het_Th2_K9me3
- GSM8241881 Het_Th2_K9me3_R2 Het_Th2_K9me3
- GSM8241882 KO_Neutral_Input_R1 KO_Neutral_Input
- GSM8241883 KO_Neutral_Input_R2 KO_Neutral_Input
- GSM8241884 KO_Neutral_K27ac_R1 KO_Neutral_K27ac
- GSM8241885 KO_Neutral_K27ac_R2 KO_Neutral_K27ac
- GSM8241886 KO_Neutral_K27me3_R1 KO_Neutral_K27me3
- GSM8241887 KO_Neutral_K27me3_R2 KO_Neutral_K27me3
- GSM8241888 KO_Neutral_K4me1_R1 KO_Neutral_K4me1
- GSM8241889 KO_Neutral_K4me1_R2 KO_Neutral_K4me1
- GSM8241890 KO_Neutral_K4me3_R1 KO_Neutral_K4me3
- GSM8241891 KO_Neutral_K4me3_R2 KO_Neutral_K4me3
- GSM8241892 KO_Neutral_K9me3_R1 KO_Neutral_K9me3
- GSM8241893 KO_Neutral_K9me3_R2 KO_Neutral_K9me3
- GSM8241894 KO_Th2_Input_R1 KO_Th2_Input
- GSM8241895 KO_Th2_Input_R2 KO_Th2_Input
- GSM8241896 KO_Th2_K27ac_R1 KO_Th2_K27ac
- GSM8241897 KO_Th2_K27ac_R2 KO_Th2_K27ac
+ 44 more — browse all 84 samples with per-sample file links →
- GSE266174 Plasticity and lineage commitment of individual Th1 cells are determined by stable T-bet expression quantities 14 samples shares plasticity, commitment, individual, determined, quantities, lineage, stable
- GSE288156 Progressive intestinal tumor cell plasticity, Myc activation and loss of Lgr5+ tumor stem cell lineage commitment upon Wnt depletion 14 samples shares plasticity, commitment, lineage
- GSE308931 Treg cells retain stable lineage commitment during pregnancy in mice after late gestation inflammatory challenge 10 samples shares commitment, lineage, stable
- GSE308575 NSD2 targeting reverses lineage plasticity and drug resistance in advanced prostate cancer [Cut&Tag] 58 samples shares plasticity, lineage
- GSE298002 Stage-specific Epigenetic Priming Amplifies Gene Activation During Lineage Commitment [CUT&Run] 38 samples shares commitment, lineage
- GSE298001 Stage-specific Epigenetic Priming Amplifies Gene Activation During Lineage Commitment [ATAC-Seq] 36 samples shares commitment, lineage
- GSE303502 EZH2 directs breast cancer progression through the modulation of epithelial cellular plasticity [ChIP-Seq] 16 samples shares plasticity, chip-seq
- GSE290751 Lineage Plasticity Driven by GATA6 Loss Fuels Colorectal Cancer Metastasis [ATAC-seq_met] 15 samples shares plasticity, lineage
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.