TGFBI is upregulated in ectopic endometrial stromal cells and under hypoxic conditions in endometriosis.
RNA-seq (gene expression) · human · 20 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 20 samples: 5 × Primary eutopic endometrial stromal cells N vs 5 × Primary ectopic endometrial stromal cells N vs 5 × Primary eutopic endometrial stromal cells H vs 5 × Primary ectopic endometrial stromal cells HGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Hypoxic conditions affect transcriptome of endometrial stromal cells in endometriosis and promote TGFBI axisFrontiers in endocrinology · 2024
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE269530_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1122200 and SRA study SRP512984. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 20 samples.
How we read this: 4 replicated groups read from 20 sample titles; they account for 20 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8319649 Primary eutopic endometrial stromal cells N1 Primary eutopic endomet…
- GSM8319650 Primary ectopic endometrial stromal cells N1 Primary ectopic endomet…
- GSM8319651 Primary eutopic endometrial stromal cells H1 Primary eutopic endomet…
- GSM8319652 Primary ectopic endometrial stromal cells H1 Primary ectopic endomet…
- GSM8319653 Primary eutopic endometrial stromal cells N2 Primary eutopic endomet…
- GSM8319654 Primary ectopic endometrial stromal cells N2 Primary ectopic endomet…
- GSM8319655 Primary eutopic endometrial stromal cells H2 Primary eutopic endomet…
- GSM8319656 Primary ectopic endometrial stromal cells H2 Primary ectopic endomet…
- GSM8319657 Primary eutopic endometrial stromal cells N3 Primary eutopic endomet…
- GSM8319658 Primary ectopic endometrial stromal cells N3 Primary ectopic endomet…
- GSM8319659 Primary eutopic endometrial stromal cells H3 Primary eutopic endomet…
- GSM8319660 Primary ectopic endometrial stromal cells H3 Primary ectopic endomet…
- GSM8319661 Primary eutopic endometrial stromal cells N4 Primary eutopic endomet…
- GSM8319662 Primary ectopic endometrial stromal cells N4 Primary ectopic endomet…
- GSM8319663 Primary eutopic endometrial stromal cells H4 Primary eutopic endomet…
- GSM8319664 Primary ectopic endometrial stromal cells H4 Primary ectopic endomet…
- GSM8319665 Primary eutopic endometrial stromal cells N5 Primary eutopic endomet…
- GSM8319666 Primary ectopic endometrial stromal cells N5 Primary ectopic endomet…
- GSM8319667 Primary eutopic endometrial stromal cells H5 Primary eutopic endomet…
- GSM8319668 Primary ectopic endometrial stromal cells H5 Primary ectopic endomet…
- GSE266265 Endometrial Insights: Unmasking Endometriosis through Single-Cell Profiling and AI-Based Prediction 60 samples shares endometriosis, endometrial
- GSE279835 miR-193b-5p and miR-374b-5p are aberrantly expressed in endometriosis and suppress endometrial cell migration in vitro 44 samples shares endometriosis, endometrial
- GSE246591 Transcriptomic exploration of decidualizing human endometrial stromal cell dynamics 40 samples shares endometrial, stromal
- GSE234338 Extracellular vesicles (EVs) secreted by human aneuploid embryos contain a distinct RNA cargo and upregulate MUC1 transcription in decidualised endometrial stromal cells (dESCs) 32 samples shares endometrial, stromal
- GSE303635 Stromal Cells from Endometriosis Patients Reflect Lesion Type-Specific Heterogeneity 20 samples shares endometriosis, stromal
- GSE325553 Comparative transcriptomic profiling of human 3D endometrial stromal organoids under distinct decidualization stimuli 20 samples shares endometrial, stromal
- GSE284362 endometriosis stromal cell with estrogen 20 samples shares endometriosis, stromal
- GSE296931 PGR Isoform Modulation via Enhancer Activation Regulates Progesterone Signaling in Human Endometrial Stromal Cells [RNA-Seq] 18 samples shares endometrial, stromal
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.