Super-enhancers reorganization controls re-sensitization of oxaliplatin-resistant FBXW7-mutated colorectal cancer
ChIP-seq / ATAC-seq (genome binding and open chromatin) · human · 10 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Homo sapiens (human)
- Samples
- 10 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Class IIa HDACs forced degradation allows resensitization of oxaliplatin-resistant FBXW7-mutated colorectal cancerMolecular oncology · 2026
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE270840_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1128608 and SRA study SRP516255. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 10 more — browse all 10 samples with per-sample file links →
- GSE256187 Super-enhancers reorganization controls re-sensitization of oxaliplatin-resistant FBXW7-mutated colorectal cancer [ChIP-seq] 20 samples shares oxaliplatin-resistant, re-sensitization, super-enhancers, reorganization, fbxw7-mutated, colorectal, controls
- GSE256188 Super-enhancers reorganization controls re-sensitization of oxaliplatin-resistant FBXW7-mutated colorectal cancer 36 samples shares oxaliplatin-resistant, re-sensitization, super-enhancers, reorganization, fbxw7-mutated, colorectal, controls
- GSE301368 Acute hormonal signaling-induced 3D chromatin loop reorganization controls adipocyte thermogenesis [ChIP-seq human] 10 samples shares reorganization, controls
- GSE314768 Transcriptomic profiling of oxaliplatin-resistant colorectal cancer cells 6 samples shares oxaliplatin-resistant, colorectal
- GSE301370 Acute hormonal signaling-induced 3D chromatin loop reorganization controls adipocyte thermogenesis [Micro-C human] 12 samples shares reorganization, controls
- GSE301359 Acute hormonal signaling-induced 3D chromatin loop reorganization controls adipocyte thermogenesis [RNA-seq human] 9 samples shares reorganization, controls
- GSE320215 Genome reorganization and its functional impact during breast cancer progression [ATAC-Seq] 6 samples shares reorganization
- GSE233299 The BET inhibitor GNE-987 effectively induces anti-cancer effects byfocusing on super-enhancers inT-cell acute lymphoblastic leukemia [Cut & Tag] 6 samples shares super-enhancers
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.